Somatic variant calling from single-cell DNA sequencing data
Computational and Structural Biotechnology Journal
Monica Valecha, David Posada
Volume 20, 2022, Pages 2978-2985, ISSN2001-0370
Monica Valecha
Bioinformatician | Computational Biologist | Cancer Genomics
Bioinformatician with more than 10 years of experience in genomics data analysis. Skilled in NGS data analysis for industry and academic research. Passionate about exploring and analyzing genomics data.
Clonality and timing of relapsing colorectal cancer metastasis revealed through whole-genome single-cell sequencing
Cancer Letters
Joao M. Alves, Sonia Prado-López, Laura Tomás, Monica Valecha, Nuria Estévez-Gómez, Pilar Alvariño, Dominik Geisel, Dominik Paul Modest, Igor M. Sauer, Johann Pratschke, Nathanael Raschzok, Christine Sers, Soulafa Mamlouk, David Posada
Volume 543, 2022, 215767, ISSN 0304-3835
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation
Nat Commun 11
Miao, K., Lei, J.H., Valecha, M.V, et al.
3256, (2020)
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy
Human Molecular Genetics
Xiaoling Xu, Eric Chen, Lihua Mo, Lei Zhang, Fangyuan Shao, Kai Miao, Jianlin Liu, Sek Man Su, Monica Valecha, Un In Chan, Hongping Zheng, Mark Chen, Weiping Chen, Qiang Chen, Haiqing Fu, Mirit I Aladjem, Yanzhen He, Chu-Xia Deng
Volume 28, Issue 5, 1 March 2019, Pages 842-857
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics
Nat Commun 12
Ren-Bo Ding, Ping Chen, Barani Kumar Rajendran, Xueying Lyu, Haitao Wang, Jiaolin Bao, Jianming Zeng, Wenhui Hao, Heng Sun, Ada Hang-Heng Wong, Monica Vishnu Valecha, Eun Ju Yang, Sek Man Su, Tak Kan Choi, Shuiming Liu, Kin Iong Chan, Ling-Lin Yang, Jingbo Wu, Kai Miao, Qiang Chen, Joong Sup Shim, Xiaoling Xu, Chu-Xia Deng.
3046, (2021)
Single-cell mtDNA heteroplasmy in colorectal cancer
Genomics 114: 110315
Almeida J, Pérez-Figueroa AP, Alves JM, Valecha M, Prado-López A, Alvarinõ P, Cameselle-Teijeiro JM, Chantada D, Fonseca MM, Posada D.
IF (2020): 5.736. Q1, INT
Towards scalable phylogeny-aware inference of single-nucleotide variations from single-cell DNA sequencing data
Bioinformatics, in press
Edrisi M, Valecha M, Chowdary SBV, Robledo S, Ogilvie HA, Posada D, Zafar H, Nakhleh L. Phylovar
IF: 6.937, D1, INT
SIEVE: joint inference of single-nucleotide variants and cell phylogeny from single- cell DNA sequencing data
bioRxiv
Senbai Kang, Nico Borgsmüller, Monica Valecha, Jack Kuipers, Joao Alves, Sonia Prado-López, Débora Chantada, Niko Beerenwinkel, David Posada, Ewa Szczurek
bioRxiv, 2022.03.24.485657;, doi:
Comparative analysis of capture methods for genomic profiling of circulating tumor cells in colorectal cancer
medRxiv
Joao M. Alves, Nuria Estévez-Gómez, Monica Valecha, Sonia Prado-López, Laura Tomás, Pilar Alvariño, Roberto Piñeiro, Laura Muinelo-Romay, Patricia Mondelo-Macía, Mercedes Salgado, Agueda Iglesias-Gómez, Laura Codesido-Prada, Joaquin Cubiella, David Posada.
medRxi, 2022.06.02.22275905, doi
Apert's syndrome: Study by whole exome sequencing
Genes & Diseases
Anjana Munshi, Preeti Khetarpal, Satrupa Das, Venkateshwar Rao, Monica Valecha, Manita Bansal, Roshan Kumar
Volume 5, Issue 2, 2018, Pages 119-122, ISSN 2352-3042